What Is Fluconazole?
Fluconazole is a potent antifungal agent, a triazole derivative. It is a selective inhibitor of sterol synthesis in the fungal cell.
How Does Fluconazole Work?
Fluconazole refers to triazole compounds by its chemical structure and is effective against various microorganisms.
The mechanism of action is based on its ability to completely inhibit and destroy the synthesis of sterols in the cells of sensitive fungi. And since sterol is one of the components of the cell, the cell wall of microorganisms simply loses its vitality.
You can take the drug with or without food. It gets into every biological fluid in the body without any problem, so its concentration in saliva and sputum will be the same as in plasma.
What Is Fluconazole Used For?
Fluconazole is presribed to treat:
- mucosal candidiasis (yeast infection);
- skin candidiasis;
- generalized and disseminated candidiasis;
- genital candidiasis;
- cutaneous mycoses (including body, feet, groin area);
Can You Buy Fluconazole Over The Counter?
You cannot buy Fluconazole over the counter in the US in the form of pills. However, creams and ointments containing Fluconazole are available OTC in most pharmacies.
Using Fluconazole pills for treating candidiasis is more effecient. In this case, you need to have a medical prescription to buy Diflucan or generic Fluconazole.
Nevertheless, you can try ordering Fluconazole over the counter online. There are a lot of Internet drugstores offering cheap Diflucan generic for sale.
If you decide to buy Diflucan over the counter online, we recommend you carefully choose your supplier to avoid getting fake or low-quality products.
What Is Candidiasis (Yeast Infection)?
Candidiasis is a pathology of the mucous membranes and skin provoked by yeast-like fungi.
Candida is always found in small amounts in healthy men and women. Their main place of localization – the mucosa of the mouth, intestines and genitals.
If there are no pathologies in the body, the process of regulating the amount of this fungus is laid down at the level of physiology.
Molluscosis or any other candidiasis indicates that the body’s immune defences have weakened and needs to be carefully diagnosed and treated.
There are various types of candidiasis:
- In the oral cavity;
- On the skin;
- In the intestine;
- Vaginal candidiasis (thrush);
- Chronic candidiasis spread throughout the body.
Many women easily recognize their thrush because they are familiar with its symptoms. The first thing that helps them suspect the disease is an intense itch felt both on the external genitals and inside the genital tract.
If thrush occurs in an acute form, then in addition to itching, the woman will suffer from swelling of the genitals, hyperemia, rashes, and an abundance of white secretions (sour smell, curd-like consistency) from the vagina. In such a condition, a woman refuses sexual intercourse because she is afraid of infecting her partner and because she cannot enjoy it in such a condition.
Fluconazole For Nail Fungus
Fluconazole copes with various diseases, including onychomycosis of the nail plates. You can cure the disease by taking a capsule of the drug once a week with a dosage of 150 mg.
Therapy should continue until the nail is restored to a healthy state. As you know, nail plates grow back in 3-6 months on the hands and 6-12 months on the feet.
Fluconazole For Thrush
Consult with your attending physician on how to use Diflucan in case of thrush. In this case, the dosage is individual.
The number of pills and the frequency of taking the drug depends on what form the disease is, how the pathological process manifests itself, and its complications.
Using Fluconazole In Women
Uncomplicated forms of candidiasis, occurring for the first time, with mild to moderate symptoms, can be treated by taking a single capsule with a dosage of 150 mg;
It is more difficult to treat candidiasis in a complicated form with clearly expressed symptoms or on the background of chronic diseases that accompany thrush. Therefore, you will have to take a Diflucan pill of the drug on the first and fourth day of treatment.
Recurrent candidiasis manifested four times a year will require taking three pills (150 mg) on the first, fourth and seventh days from the start of treatment. In addition, your sexual partner will need to take a capsule once.
Using Fluconazole In Men
Candida fungi are unknown to take root in the male urethra because they are washed out regularly by urine. But when the male immune system weakens, there are no obstacles to the development of urogenital candidiasis. And men may wonder: can they also take Fluconazole?
This drug is absorbed into the bloodstream, where it is distributed evenly in men’s body fluids. It does not change the hormonal background in any way. Therefore, may also use a single pill of Fluconazole 150mg to treat candidiasis.
Avoid using Fluconazole if you have:
- Individual hypersensitivity to the main active substance or additional components;
- Lactose deficiency or lactose intolerance;
- Glucose-galactose malabsorption syndrome;
- Children under 3 years.
Use the drug with caution in case of:
- hepatic or renal insufficiency;
- if you have a risk of arrhythmia;
You may have the following side effects when using Fluconazole:
- Digestive system: nausea and diarrhoea, bloating.
- Blood system: leukopenia, thrombocytopenia, agranulocytosis.
- Nervous system: dizziness and headaches.
- Allergies: skin rash and anaphylactic reactions.
You may also experience the following side effects when administering the drug intravenously:
- Digestive system: flatulence, nausea with vomiting, hepatic functional failure.
- Cardiovascular system: fibrillation or even ventricular flutter.
- Nervous system: headaches, convulsive seizures.
- Allergic reactions: skin rash, toxic epidermal necrosis, Lyell and Stevens-Jonas syndromes, anaphylactic reactions.
- Other systems: renal failure, alopecia.
Pregnancy And Breastfeeding
Fluconazole is not a safe drug for pregnant and breastfeeding women.
Therefore, doctors prescribe it to women in this special condition only if the potential benefits to the mother significantly exceed the possible risk to the baby.
In addition, general side effects do not bypass a woman when used during pregnancy, which is additional stress to the body.
Fluconazole is found in mother’s milk in the same concentration as in the blood. That is why you have to stop breastfeeding during the treatment.